Description

Cdc7-In-6 CAS NO 1402057-88-8 is a potent and selective small-molecule inhibitor of the cell division cycle 7 (Cdc7) kinase, a key regulator of DNA replication initiation. This compound matters for researchers and developers in oncology and cell biology, as it provides a critical tool for investigating cell cycle control mechanisms and validating Cdc7 as a therapeutic target in cancer. Pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel anti-cancer agents are the primary users of this high-purity biochemical.

Application

• Biochemical Research: Used as a selective probe to study the role of Cdc7 kinase in DNA replication, cell cycle progression, and checkpoint signaling in vitro.
• Oncology Drug Discovery: Serves as a reference compound and a starting point for the development of novel Cdc7-targeted anti-cancer therapeutics.
• Cell Biology Studies: Employed to investigate the consequences of Cdc7 inhibition on cell proliferation, apoptosis, and genomic stability in various cancer cell lines.
• Mechanism of Action (MoA) Studies: Utilized to validate Cdc7 as a critical target and to understand resistance mechanisms in preclinical cancer models.
• High-Throughput Screening (HTS): Can be used as a control or standard in screening assays designed to identify new Cdc7 inhibitors or modulators.

Basic Information

Product Name	Cdc7-In-6
CAS No.	1402057-88-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cdc7 Inhibitor 6; CDC7-IN-6; 1402057-88-8; Cdc7 Kinase Inhibitor; Cdc7i-6
EINECS	Contact for details

Quality Control

Our Cdc7-In-6 is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results for your records and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.