Description

2-(1,1-Difluoroethyl)-4-Methyl-Pyridine is a high-value, fluorinated pyridine derivative, identified by CAS NO 1401425-30-6. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used as a building block for developing next-generation herbicides and pesticides, where the difluoroethyl group can improve bioavailability and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating novel nitrogen-containing ligands used in transition metal catalysis for fine chemical production.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced materials requiring specific fluorinated aromatic components.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on introducing fluorine atoms into complex molecular architectures.

Basic Information

Product Name	2-(1,1-Difluoroethyl)-4-Methyl-Pyridine
CAS No.	1401425-30-6
Molecular Formula	C8H9F2N
Molecular Weight	157.16 g/mol
Synonyms	4-Methyl-2-(1,1-difluoroethyl)pyridine; 2-(1,1-Difluoroethyl)-4-picoline; 4-Methyl-2-(α,α-difluoroethyl)pyridine; 2-(Difluoroethyl)-4-methylpyridine; 1401425-30-6; 4-Methyl-2-(1,1-difluoroethyl)pyridine
EINECS	Contact for details

Quality Control

Our production of 2-(1,1-Difluoroethyl)-4-Methyl-Pyridine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.