Description

3-{10-Fluoro-2,4-Dimethylpyrimido[1,2-B]Indazol-3-Yl}Propanoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• API Development: Serves as a critical precursor in the multi-step synthesis of complex target molecules for preclinical and clinical development.
• Biochemical Tool Compound: Potential use in biochemical assays and as a probe for studying specific biological interactions in academic and industrial research.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3-{10-Fluoro-2,4-Dimethylpyrimido[1,2-B]Indazol-3-Yl}Propanoic Acid
CAS No.	1401319-37-6
Molecular Formula	C₁₆H₁₅FN₄O₂
Molecular Weight	314.32 g/mol
Synonyms	3-(10-Fluoro-2,4-dimethylpyrimido[1,2-b]indazol-3-yl)propanoic acid; 10-Fluoro-2,4-dimethyl-3-(2-carboxyethyl)pyrimido[1,2-b]indazole; 1401319-37-6; 3-(10-Fluoro-2,4-dimethylpyrimido[1,2-b]indazol-3-yl)propionic acid; Propanoic acid, 3-(10-fluoro-2,4-dimethylpyrimido[1,2-b]indazol-3-yl)-
EINECS	Contact for details

Quality Control

Our 3-{10-Fluoro-2,4-Dimethylpyrimido[1,2-B]Indazol-3-Yl}Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.