Description

(5-Trifluoromethyl-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester CAS NO 1399664-49-3 is a high-value, fluorinated pyridine derivative used as a critical building block in advanced organic synthesis. Its core value lies in providing a protected amine group and a versatile trifluoromethylpyridine scaffold, enabling the efficient development of novel compounds with enhanced properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is utilized to create active ingredients with improved metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group contributes to lipophilicity and biological activity.
• Material Science Research: Serves as a precursor for creating specialty chemicals, ligands, and functional materials with unique electronic properties.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	(5-Trifluoromethyl-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	1399664-49-3
Molecular Formula	C11H13F3N2O2
Molecular Weight	262.23 g/mol
Synonyms	tert-Butyl (5-(trifluoromethyl)pyridin-2-yl)carbamate; N-Boc-2-Amino-5-trifluoromethylpyridine; 2-((tert-Butoxycarbonyl)amino)-5-(trifluoromethyl)pyridine; 5-Trifluoromethyl-2-pyridinylcarbamic Acid 1,1-Dimethylethyl Ester; Boc-2-Amino-5-trifluoromethylpyridine; N-Boc-5-Trifluoromethyl-2-aminopyridine; 2-N-Boc-Amino-5-trifluoromethylpyridine; (5-Trifluoromethyl-2-pyridinyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our (5-Trifluoromethyl-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and full characterization data are provided with every shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.