Description

Diphenyl Phthalate-3,4,5,6-D4 is a deuterated isotopologue of diphenyl phthalate, a compound of significant interest in analytical and research chemistry. This deuterium-labeled version is specifically designed for use as an internal standard in mass spectrometry and other quantitative analytical techniques, where it provides enhanced accuracy and reliability by compensating for matrix effects and instrument variability. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, environmental, and material science sectors who require precise quantification of phthalate compounds.

Application

• Primary use as an internal standard for LC-MS/MS and GC-MS analysis of phthalates and related esters.
• Critical component in deuterium-labeled standard mixtures for environmental testing of plasticizers.
• Used in metabolomics and pharmacokinetic studies to track the absorption and distribution of phthalate derivatives.
• Facilitates stable isotope dilution assays in food safety and regulatory compliance testing.
• Supports polymer research and development, particularly in studying plasticizer migration and degradation.
• Enables high-precision quantitative NMR (qNMR) applications due to its defined isotopic enrichment.

Basic Information

Product Name	Diphenyl Phthalate-3,4,5,6-D4
CAS No.	1398065-61-6
Molecular Formula	C20H10D4O4
Molecular Weight	322.34 g/mol
Synonyms	1,2-Benzenedicarboxylic acid, 3,4,5,6-tetradeuterio-, 1,2-diphenyl ester; Diphenyl benzene-3,4,5,6-d4-1,2-dicarboxylate; Phthalic acid-d4 diphenyl ester; Diphenyl phthalate-d4; DPP-d4; Deuterated Diphenyl Phthalate (3,4,5,6-D4); Isotopically Labeled Diphenyl Phthalate
EINECS	Contact for details

Quality Control

Every batch of Diphenyl Phthalate-3,4,5,6-D4 is produced and tested to meet exacting standards for isotopic purity and chemical identity. Our quality assurance protocol includes verification of deuterium incorporation, chemical purity, and absence of interfering impurities. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as isotopic enrichment (atom % D), chemical purity by HPLC, and confirmatory data from NMR and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0% (3,4,5,6 positions)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.