Description

2-Bromo-4-Chloro-5-Iodobenzotrifluoride is a high-purity, multi-halogenated aromatic building block of significant synthetic utility. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, particularly in the development of complex molecules. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for constructing specialized fluorinated and halogenated target compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing trifluoromethyl and halogen substituents for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, where the unique halogen pattern can influence selectivity and potency.
• Material Science Research: Serves as a precursor for developing advanced organic electronic materials, liquid crystals, and specialty polymers that require precise halogen and fluorine substitution.
• Cross-Coupling Reactions: An excellent substrate for various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) due to the presence of bromo and iodo leaving groups, enabling diverse molecular architectures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for imaging, diagnostics, and studying biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies and CROs/CMOs engaged in custom synthesis projects for clients in life sciences.

Basic Information

Item	Detail
Product Name	2-Bromo-4-Chloro-5-Iodobenzotrifluoride
CAS No.	1394291-54-3
Molecular Formula	C7H2BrClF3I
Molecular Weight	399.35 g/mol
Synonyms	1-Bromo-2-chloro-4-iodo-5-(trifluoromethyl)benzene; 2-Bromo-4-chloro-1-iodo-5-(trifluoromethyl)benzene; 2-Bromo-4-chloro-5-iodobenzotrifluoride; 2-Bromo-4-chloro-5-iodo-α,α,α-trifluorotoluene; Benzene, 1-bromo-2-chloro-4-iodo-5-(trifluoromethyl)-; 5-Iodo-2-bromo-4-chlorobenzotrifluoride
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Chloro-5-Iodobenzotrifluoride is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.