Description

1-Bromo-3-Fluoro-2-Methoxy-5-Methylbenzene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique substitution pattern, which allows for selective cross-coupling reactions and further functionalization. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those requiring specific halogenated aromatic cores for bioactivity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the bromo and fluoro substituents are crucial for efficacy.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the reactive bromine atom.
• Chemical Library Development: Employed in medicinal chemistry for the parallel synthesis and diversification of compound libraries for high-throughput screening.
• Fluorinated Compound Synthesis: Acts as a starting material for introducing fluorine atoms into more complex molecular architectures.

Basic Information

Product Name	1-Bromo-3-Fluoro-2-Methoxy-5-Methylbenzene
CAS No.	1394291-45-2
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	2-Bromo-6-Fluoro-3-Methoxytoluene; 3-Bromo-1-Fluoro-2-Methoxy-5-Methylbenzene; Benzene, 1-bromo-3-fluoro-2-methoxy-5-methyl-; 5-Methyl-3-fluoro-2-methoxybromobenzene; 2-Methoxy-6-methyl-3-fluorobromobenzene; 1-Bromo-3-fluoro-2-methoxy-5-methyl-benzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Fluoro-2-Methoxy-5-Methylbenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.