Description

5-Methyl-3-(Trifluoromethyl)Pyridin-2-Ol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethyl group and a hydroxyl substituent on the pyridine ring, makes it an essential intermediate for developing novel compounds with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in areas requiring fluorinated motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can enhance activity and environmental profile.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Methyl-3-(Trifluoromethyl)Pyridin-2-Ol
CAS No.	1394021-29-4
Molecular Formula	C7H6F3NO
Molecular Weight	177.12 g/mol
Synonyms	2-Hydroxy-5-methyl-3-(trifluoromethyl)pyridine; 3-(Trifluoromethyl)-5-methylpyridin-2-ol; 5-Methyl-3-trifluoromethyl-2-pyridinol; 2-Pyridinol, 5-methyl-3-(trifluoromethyl)-; 5-Methyl-3-(trifluoromethyl)-2-hydroxypyridine
EINECS	Contact for details

Quality Control

Our 5-Methyl-3-(Trifluoromethyl)Pyridin-2-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.