Description

Oxetane-3-Sulfonyl Chloride is a high-value, reactive sulfonyl chloride derivative featuring a strained oxetane ring. This compound serves as a critical versatile building block in advanced organic synthesis, enabling the introduction of the sulfonyl chloride functional group alongside a polar, three-dimensional oxetane moiety. It is primarily utilized by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, as well as by researchers in material science exploring new polymers and functional materials.

Application

• Pharmaceutical Intermediates: Key synthon for constructing sulfonamide-based drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides where the oxetane ring can modulate physicochemical properties.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for synthesizing specialty polymers with tailored thermal and mechanical properties.
• Chemical Biology: Employed as a reactive handle for bioconjugation and probe development due to its electrophilic sulfonyl chloride group.
• Material Science: Building block for advanced materials such as sulfonated membranes or coatings.
• Organic Synthesis: Versatile reagent for introducing the oxetane-3-sulfonyl moiety into complex molecular architectures.

Basic Information

Product Name	Oxetane-3-Sulfonyl Chloride
CAS No.	1393585-06-2
Molecular Formula	C3H5ClO3S
Molecular Weight	156.59 g/mol
Synonyms	3-Oxetanesulfonyl chloride; Oxetan-3-ylsulfonyl chloride; 3-Sulfonylchloride oxetane; Oxetane sulfonyl chloride; 1-Oxa-2-thiacyclobutane 2,2-dioxide, 4-chloro-; 3-Oxetanyl sulfonyl chloride; (Oxetan-3-yl)sulfonyl chloride; 3-Oxetanesulfonic acid chloride
EINECS	Contact for details

Quality Control

Our Oxetane-3-Sulfonyl Chloride is manufactured under strict quality protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture ingress and decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.