Description

1-(4-Chloro-3-Fluoropyridin-2-Yl)Ethanone is a high-purity fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated structure, which enables precise molecular modifications in the development of active pharmaceutical ingredients and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active molecule research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluoropyridine moiety for enhanced efficacy and environmental profile.
• Material Science Precursor: Serves as a starting material for synthesizing functionalized ligands and complexing agents used in catalysis and advanced polymers.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new chemical reactions and building complex heterocyclic frameworks.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	1-(4-Chloro-3-Fluoropyridin-2-Yl)Ethanone
CAS No.	1393572-94-5
Molecular Formula	C7H5ClFNO
Molecular Weight	173.57 g/mol
Synonyms	2-Acetyl-4-chloro-3-fluoropyridine; 4-Chloro-3-fluoro-2-acetylpyridine; 1-(4-Chloro-3-fluoropyridin-2-yl)ethan-1-one; Ethanone, 1-(4-chloro-3-fluoro-2-pyridinyl)-; 4-Chloro-3-fluoro-2-pyridinyl methyl ketone
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-3-Fluoropyridin-2-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.