Description

4-Chloro-5-Fluoropyridin-2-Amine is a high-purity, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents on the pyridine core, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for developing new generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the creation of specialized ligands, functionalized polymers, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes, tags, and inhibitors for biological target identification.
• Custom Synthesis & Contract Manufacturing: Essential starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	4-Chloro-5-Fluoropyridin-2-Amine
CAS No.	1393562-83-8
Molecular Formula	C5H4ClFN2
Molecular Weight	146.55 g/mol
Synonyms	2-Amino-4-chloro-5-fluoropyridine; 5-Fluoro-4-chloropyridin-2-amine; 4-Chloro-5-fluoro-2-pyridinamine; 4-Chloro-5-fluoro-2-aminopyridine; 2-Pyridinamine, 4-chloro-5-fluoro-; 1393562-83-8
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Fluoropyridin-2-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch, and our quality systems support compliance with relevant regulatory frameworks for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.