Description

5-(Aminomethyl)-2,1-Benzoxaborol-1(3H)-Ol Hydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is of significant commercial interest due to its role as a key building block in the synthesis of novel benzoxaborole-based therapeutics. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of next-generation benzoxaborole-based drugs, particularly antifungal and anti-inflammatory agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel boron-containing bioactive molecules.
• Protease Inhibitor Development: Serves as a precursor for compounds targeting serine proteases and other enzymes where the boronic acid pharmacophore is effective.
• Bioconjugation & Probe Synthesis: The aminomethyl group enables conjugation to peptides, proteins, or fluorescent tags for biochemical and diagnostic applications.
• Library Synthesis for High-Throughput Screening: Used to create diverse compound libraries for screening against various biological targets.
• Academic & Institutional Research: Fundamental research into the unique reactivity and biological activity of benzoxaborole scaffolds.

Basic Information

Product Name	5-(Aminomethyl)-2,1-Benzoxaborol-1(3H)-Ol Hydrochloride
CAS No.	1393477-25-2
Molecular Formula	C8H11BClNO2
Molecular Weight	199.44 g/mol
Synonyms	1,3-Dihydro-5-(aminomethyl)-2,1-benzoxaborol-1-ol hydrochloride; 5-(Aminomethyl)-1-hydroxy-1,3-dihydro-2,1-benzoxaborole hydrochloride; 5-(Aminomethyl)-2,1-benzoxaborol-1(3H)-ol HCl; 1-Hydroxy-5-(aminomethyl)-1,3-dihydro-2,1-benzoxaborole hydrochloride; Benzoxaborole-aminomethyl hydrochloride derivative; AN2690 intermediate hydrochloride; Tavaborole precursor salt
EINECS	Contact for details

Quality Control

Our 5-(Aminomethyl)-2,1-Benzoxaborol-1(3H)-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.