Description

3-(n-Acetyl-L-Cystein-S-Yl) Acetaminophen, Methyl Ester is a specialized synthetic intermediate of significant interest in pharmaceutical research and development. This compound is primarily valued for its role as a key building block in the synthesis of novel drug candidates and for use in metabolic and biochemical studies. It is particularly relevant for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, well-characterized intermediates for advanced synthesis and analytical applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in metabolic pathway studies, enzyme inhibition assays, and the investigation of drug metabolism and disposition.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Prodrug Development: Investigated for the design of prodrugs aimed at improving drug delivery, bioavailability, and targeting.
• Conjugate Synthesis: Employed in the creation of drug conjugates, including antibody-drug conjugates (ADCs) and other targeted delivery systems.
• Academic & Industrial R&D: Essential for medicinal chemistry programs and discovery research in both academic institutions and corporate R&D laboratories.

Basic Information

Product Name	3-(n-Acetyl-L-Cystein-S-Yl) Acetaminophen, Methyl Ester
CAS No.	1391068-08-8
Molecular Formula	C14H18N2O5S
Molecular Weight	326.37 g/mol
Synonyms	N-Acetyl-S-(4-(methoxycarbonyl)phenyl)-L-cysteine; APAP-Cys Methyl Ester; Acetaminophen-Cysteine Methyl Ester Conjugate; Methyl 2-(Acetylamino)-3-[[4-(methoxycarbonyl)phenyl]sulfanyl]propanoate; 3-[(4-(Methoxycarbonyl)phenyl)thio]-N-acetyl-L-alanine Methyl Ester; N-Acetyl-3-((4-(methoxycarbonyl)phenyl)thio)-L-alanine Methyl Ester
EINECS	Contact for details

Quality Control

Our 3-(n-Acetyl-L-Cystein-S-Yl) Acetaminophen, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.