Description

4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-Pentamethyl-2-Naphthalenyl)Carbonyl]-Benzoic Acid Methyl Ester -13C4 is a stable isotope-labeled derivative of a naphthalene-based compound, serving as a critical internal standard for precise quantitative analysis. This high-purity labeled compound is essential for ensuring accuracy and reliability in sensitive analytical methods, particularly in research and development. It is primarily required by analytical laboratories and pharmaceutical R&D teams working on method development, pharmacokinetic studies, and metabolite identification.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference in LC-MS and GC-MS analysis to correct for instrument variability and sample preparation losses.
• Pharmaceutical Research & Metabolite Tracing: Enables the accurate tracking and quantification of drug metabolites in biological matrices during ADME (Absorption, Distribution, Metabolism, and Excretion) studies.
• Method Development & Validation: Critical for developing and validating robust, high-precision analytical methods in compliance with regulatory guidelines (e.g., ICH, FDA).
• Environmental & Food Safety Analysis: Supports the detection and quantification of trace-level contaminants or compounds in complex sample matrices.
• Isotope Dilution Analysis (IDA): Employed in this gold-standard technique for achieving the highest possible accuracy in quantitative measurements.
• Biochemical Research: Facilitates mechanistic studies in biochemistry where precise quantification of specific pathways or compounds is necessary.

Basic Information

Product Name	4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-Pentamethyl-2-Naphthalenyl)Carbonyl]-Benzoic Acid Methyl Ester -13C4
CAS No.	1391054-72-0
Molecular Formula	C24H30O3-13C4
Molecular Weight	~390.5 g/mol (Contact for exact value)
Synonyms	Methyl 4-[(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)carbonyl]benzoate-13C4; 13C4-Labeled TTNPB methyl ester; 13C4-Arotinoid methyl ester; Methyl 13C4-4-[(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)carbonyl]benzoate; 13C4-Labeled Retinoid analog; Benzoic acid, 4-[(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]-, methyl ester-13C4; 13C4 Isotopologue of TTNPB Me ester
EINECS	Contact for details

Quality Control

Every batch of our 13C4-labeled compound is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity through advanced analytical techniques including NMR, HPLC, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and identity confirmation is provided with each shipment to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C to maintain optimal stability and isotopic integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.