Description

5-Chloro-1-Methylimidazole-13C4 is a stable isotope-labeled analog of a key heterocyclic building block, where four carbon atoms are replaced with the carbon-13 isotope. This compound is essential for creating internal standards and labeled tracers used in advanced analytical techniques, ensuring precise and reliable quantitative measurements. It is primarily required by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for drug metabolism studies, environmental fate analysis, and high-accuracy mass spectrometry.

Application

• Internal Standard for LC-MS/MS: Serves as a critical quantitative reference standard in liquid chromatography-tandem mass spectrometry for pharmacokinetic and bioanalytical studies.
• Metabolite Tracing in Drug Development: Used to label and track the metabolic pathways and degradation products of active pharmaceutical ingredients (APIs).
• Isotope Dilution Mass Spectrometry (IDMS): Enables highly accurate quantification of target analytes in complex matrices, improving method validation.
• Synthesis of Labeled Agrochemicals: Acts as a building block for creating carbon-13 labeled pesticides or herbicides for environmental fate and residue analysis studies.
• Biochemical Research Probes: Utilized in mechanistic studies to investigate biochemical pathways and enzyme interactions involving imidazole-based compounds.
• Quality Control & Method Development: Supports the development and verification of robust analytical methods in contract research organizations (CROs) and quality control labs.

Basic Information

Product Name	5-Chloro-1-Methylimidazole-13C4
CAS No.	1391052-92-8
Molecular Formula	C413C1H5ClN2
Molecular Weight	~131.55 g/mol
Synonyms	1-Methyl-5-chloroimidazole-13C4; 5-Chloro-1-methyl-1H-imidazole-13C4; 5-Chloro-1-methylimidazole (13C4); 1H-Imidazole, 5-chloro-1-methyl-13C4; 13C4-Labeled 5-Chloro-1-methylimidazole; Isotopically labeled 5-chloro-1-methylimidazole; 5-Chloro-N-methylimidazole-13C4
EINECS	Contact for details

Quality Control

Our 5-Chloro-1-Methylimidazole-13C4 is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (atom % 13C), chemical purity by HPLC, and identity confirmation. We support compliance with relevant GMP and ISO guidelines for research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.