Description

3-(2,6-Dichlorophenyl)-5-Methyl-4-Isoxazolylcarboxylic-13C4 Acid Methyl Ester is a stable isotope-labeled compound, specifically a carbon-13 (13C) labeled analog, which is essential for advanced analytical and research applications. This high-purity chemical serves as a critical internal standard and tracer in quantitative mass spectrometry, enabling precise measurement and metabolic pathway elucidation. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers engaged in drug metabolism and pharmacokinetics (DMPK) studies, bioanalytical method development, and environmental fate analysis.

Application

• Used as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS/MS) for the accurate quantification of its unlabeled counterpart or related metabolites.
• Critical for conducting stable isotope dilution assays to enhance analytical precision and accuracy in complex biological matrices.
• Employed in pharmacokinetic and drug metabolism studies to trace absorption, distribution, metabolism, and excretion (ADME) pathways.
• Facilitates metabolite identification and profiling in pre-clinical and clinical research.
• Applied in environmental analysis as a tracer to study the degradation and fate of similar chemical structures.
• Serves as a key building block or reference material in the synthesis of other isotopically labeled compounds for research.

Basic Information

Product Name	3-(2,6-Dichlorophenyl)-5-Methyl-4-Isoxazolylcarboxylic-13C4 Acid Methyl Ester
CAS No.	1391052-23-5
Molecular Formula	C1213C4H11Cl2NO3
Molecular Weight	Contact for details
Synonyms	Methyl 3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxylate-13C4; Methyl 3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carboxylate-13C4; 13C4-Labeled 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolecarboxylic acid methyl ester; Isoxazolylcarboxylic-13C4 Acid Methyl Ester Derivative; Stable Isotope Labeled Isoxazole Ester; 1391052-23-5 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Every batch of our 3-(2,6-Dichlorophenyl)-5-Methyl-4-Isoxazolylcarboxylic-13C4 Acid Methyl Ester is manufactured and analyzed under strict quality management systems. We guarantee high chemical purity and isotopic enrichment, with specifications typically meeting or exceeding the requirements for research and analytical use. Certificates of Analysis (COA) are provided for each lot, detailing key parameters such as assay (HPLC), isotopic purity (NMR/MS), and chemical purity. Our commitment ensures reliable and consistent performance for your most sensitive applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (13C)	≥ 99 atom % 13C
Isotopic Enrichment	≥ 99% on four labeled positions
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.