Description

4-[(5-Methyl-3-Phenyl-4-Isoxazolyl)Methyl]Benzenesulfonyl Chloride is a high-value, specialized sulfonyl chloride derivative that serves as a critical building block in advanced organic synthesis. Its core value lies in its dual functionality, combining a reactive sulfonyl chloride group with a substituted isoxazole scaffold, enabling the construction of complex molecules with targeted properties. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for creating sulfonamide-based molecules with biological activity.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides by incorporating the isoxazole-sulfonyl pharmacophore.
• Material Science: Employed in the production of specialty polymers and advanced materials where the sulfonyl chloride group facilitates cross-linking or functionalization.
• Chemical Biology Probes: Serves as a reagent for modifying proteins or other biomolecules to study biological pathways and interactions.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for client-specific, multi-step synthetic routes.

Basic Information

Product Name	4-[(5-Methyl-3-Phenyl-4-Isoxazolyl)Methyl]Benzenesulfonyl Chloride
CAS No.	1391051-82-3
Molecular Formula	C17H14ClNO3S
Molecular Weight	347.81 g/mol
Synonyms	4-[(5-Methyl-3-phenyl-4-isoxazolyl)methyl]benzenesulfonyl chloride; 4-((5-Methyl-3-phenylisoxazol-4-yl)methyl)benzenesulfonyl chloride; Benzenesulfonyl chloride, 4-[(5-methyl-3-phenyl-4-isoxazolyl)methyl]-; 1391051-82-3; 4-(5-Methyl-3-phenylisoxazole-4-carbonyl)benzenesulfonyl chloride (common misnomer); Isoxazole sulfonyl chloride derivative
EINECS	Contact for details

Quality Control

Every batch of 4-[(5-Methyl-3-Phenyl-4-Isoxazolyl)Methyl]Benzenesulfonyl Chloride is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.