Description

3,5-Difluoro-4-(Trifluoromethyl)Pyridine is a high-value, multi-fluorinated pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both difluoro and trifluoromethyl substituents, provides exceptional electronic properties and metabolic stability, making it indispensable for creating novel compounds with enhanced performance. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the creation of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity, bioavailability, and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis, enabling more efficient and selective chemical transformations.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and electronic materials that require specific fluorine-based properties.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3,5-Difluoro-4-(Trifluoromethyl)Pyridine
CAS No.	1391033-20-7
Molecular Formula	C7H2F5N
Molecular Weight	195.09 g/mol
Synonyms	4-(Trifluoromethyl)-3,5-difluoropyridine; 3,5-Difluoro-4-trifluoromethylpyridine; Pyridine, 3,5-difluoro-4-(trifluoromethyl)-; 1391033-20-7
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the presence of fluorine, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.