Description

1-Bromo-3-Fluoro-5-(Methoxymethyl)Benzene is a high-purity halogenated benzene derivative, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in the strategic positioning of bromine, fluorine, and methoxymethyl functional groups, which enable precise molecular modifications and the introduction of specific physicochemical properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated and brominated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating advanced organic electronic materials and liquid crystal compounds due to its substituted benzene structure.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form complex biaryl structures.
• Functional Polymer Monomer: Employed in the synthesis of specialty polymers and dendrimers with tailored properties for high-performance applications.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries for screening.

Basic Information

Item	Details
Product Name	1-Bromo-3-Fluoro-5-(Methoxymethyl)Benzene
CAS No.	1383985-25-8
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	3-Bromo-5-fluoroanisole, methoxymethyl derivative; 5-Bromo-1-fluoro-3-(methoxymethyl)benzene; 1-Bromo-3-fluoro-5-methoxymethylbenzene; (3-Bromo-5-fluorophenyl)methanol methyl ether; Benzene, 1-bromo-3-fluoro-5-(methoxymethyl)-; 3-Fluoro-5-methoxymethylbromobenzene; 5-(Methoxymethyl)-1-bromo-3-fluorobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Fluoro-5-(Methoxymethyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for GMP-grade intermediates used in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container must be kept tightly closed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.