Description

n-[4-[(Dimethylamino)Sulfonyl]Phenyl]-4-(Hydroxydiphenylmethyl)-1-Piperidinecarbothioamide is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is critical for synthesizing novel therapeutic agents, particularly in the fields of central nervous system (CNS) and metabolic disorder research. It is essential for pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in the development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).

Application

• Key intermediate in the synthesis of novel pharmaceutical candidates targeting neurological pathways.
• Building block for research into potent and selective enzyme inhibitors.
• Precursor in the development of CNS-active compounds for potential treatment of disorders like Alzheimer's and Parkinson's disease.
• Used in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Critical material for process chemistry and scale-up optimization in API manufacturing.
• Reference standard for analytical method development and quality control in pharmaceutical labs.

Basic Information

Product Name	n-[4-[(Dimethylamino)Sulfonyl]Phenyl]-4-(Hydroxydiphenylmethyl)-1-Piperidinecarbothioamide
CAS No.	1383478-94-1
Molecular Formula	C27H31N3O3S2
Molecular Weight	509.68 g/mol
Synonyms	4-(Hydroxydiphenylmethyl)-N-[4-(dimethylsulfamoyl)phenyl]-1-piperidinecarbothioamide; 1-Piperidinecarbothioamide, N-[4-[(dimethylamino)sulfonyl]phenyl]-4-(hydroxydiphenylmethyl)-; CAS 1383478-94-1; 4-(Hydroxydiphenylmethyl)-N-[4-(dimethylsulfamoyl)phenyl]piperidine-1-carbothioamide; Advanced Pharmaceutical Intermediate 1383478-94-1; CNS Research Intermediate
EINECS	Contact for details

Quality Control

Our n-[4-[(Dimethylamino)Sulfonyl]Phenyl]-4-(Hydroxydiphenylmethyl)-1-Piperidinecarbothioamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or storing under an inert atmosphere to prevent oxidation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.