Description

6-Carboxytetramethylrhodamine-Peg3-Azide (6-Tamra-Peg3-Azide) is a high-purity, multifunctional fluorescent dye derivative designed for advanced bioconjugation and labeling applications. This compound is engineered to provide a robust and versatile linker for click chemistry, enabling precise attachment of biomolecules for imaging and diagnostic purposes. It is an essential reagent for researchers and developers in the fields of biopharmaceuticals, proteomics, and in vitro diagnostics, where reliable fluorescent tagging is critical.

Application

• Bioconjugation and Labeling: Used for site-specific fluorescent labeling of proteins, antibodies, peptides, and oligonucleotides via copper-free click chemistry.
• Bioimaging Probes: Serves as a key component in the synthesis of fluorescent probes for live-cell imaging, super-resolution microscopy, and in vivo tracking.
• Diagnostic Assay Development: Enables the creation of highly sensitive detection systems for ELISA, lateral flow assays, and other diagnostic platforms.
• Drug Discovery & Development: Facilitates the study of drug-target interactions, cellular uptake, and biodistribution through fluorescent tagging of candidate molecules.
• Polymer and Material Science: Acts as a functional monomer or cross-linker for creating fluorescent hydrogels, nanoparticles, and smart polymeric materials.
• Chemical Biology Research: A critical tool for activity-based protein profiling (ABPP), metabolic labeling, and other advanced chemical biology techniques.

Basic Information

Product Name	6-Carboxytetramethylrhodamine-Peg3-Azide (6-Tamra-Peg3-Azide)
CAS No.	1380486-02-1
Molecular Formula	C41H48N6O10
Molecular Weight	784.87 g/mol
Synonyms	6-TAMRA-PEG3-Azide; 6-Carboxy-TAMRA-PEG3-N3; 5(6)-Carboxytetramethylrhodamine-triethyleneglycol-azide; TAMRA Azide PEG3; Rhodamine 6G derivative, PEG3 azide; 6-TAMRA-PEG3-N3; 6-Carboxy-TMR-PEG3-Azide; Azido-PEG3-6-carboxytetramethylrhodamine
EINECS	Contact for details

Quality Control

Our 6-Tamra-Peg3-Azide is manufactured under strict quality systems to ensure batch-to-batch consistency and high performance. Each lot undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and NMR for structural verification. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to quality standards suitable for research and development use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Dark red to purple solid or film
Identification (HPLC/MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.