Description

6-Bromo-3-Fluoropyridin-2-Amine is a high-purity, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both bromine and fluorine substituents on an aminopyridine core, makes it an indispensable intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated pyridines.
• Material Science Precursor: Serves as a building block for synthesizing functionalized ligands, organic semiconductors, and liquid crystal materials.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for Suzuki, Stille, and Buchwald-Hartwig cross-coupling reactions to create biaryl and other complex structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and diagnostic applications.

Basic Information

Product Name	6-Bromo-3-Fluoropyridin-2-Amine
CAS No.	1379457-78-9
Molecular Formula	C5H4BrFN2
Molecular Weight	191.00 g/mol
Synonyms	2-Amino-6-bromo-3-fluoropyridine; 3-Fluoro-6-bromopyridin-2-amine; 6-Bromo-3-fluoro-2-pyridinamine; 2-Pyridinamine, 6-bromo-3-fluoro-; 6-Bromo-3-fluoro-2-aminopyridine
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Fluoropyridin-2-Amine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.