Description

4-(Bromomethyl)-2-Fluorobenzaldehyde is a versatile and high-value aromatic aldehyde building block. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine and bromine substituents for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as fluorinated polymers and liquid crystals, where the aldehyde group allows for further functionalization.
• Cross-Coupling Reactions: The bromomethyl group makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to build complex biaryl systems.
• Fluorine Chemistry Studies: Acts as a model compound for studying the electronic effects of ortho-fluorine substitution on aromatic aldehyde reactivity.

Basic Information

Product Name	4-(Bromomethyl)-2-Fluorobenzaldehyde
CAS No.	1379307-40-0
Molecular Formula	C8H6BrFO
Molecular Weight	217.04 g/mol
Synonyms	2-Fluoro-4-(bromomethyl)benzaldehyde; 4-Bromomethyl-2-fluorobenzaldehyde; 2-Fluoro-4-bromomethylbenzaldehyde; (2-Fluoro-4-formylphenyl)methyl bromide; Benzaldehyde, 4-(bromomethyl)-2-fluoro-; 4-Bromomethyl-2-fluorobenzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-(Bromomethyl)-2-Fluorobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize oxidation and degradation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.