Description

8-Bromo-5-Fluoroisoquinoline is a high-purity, halogenated isoquinoline derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it an invaluable scaffold for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for drug discovery and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the fluorinated isoquinoline core.
• Material Science: Serves as a monomer or functional unit in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology: Employed as a probe or labeling agent in biochemical assays and diagnostic research due to its halogen tags.
• Academic & R&D: A versatile reagent for methodological development in organic chemistry, including cross-coupling reactions and heterocyclic chemistry studies.

Basic Information

Product Name	8-Bromo-5-Fluoroisoquinoline
CAS No.	1378874-27-1
Molecular Formula	C9H5BrFN
Molecular Weight	226.05 g/mol
Synonyms	5-Fluoro-8-bromoisoquinoline; 8-Bromo-5-fluoro-isoquinoline; Isoquinoline, 8-bromo-5-fluoro-; 1378874-27-1; 8-Br-5-F-IQ
EINECS	Contact for details

Quality Control

Our 8-Bromo-5-Fluoroisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.