Description

4-Methyl-2-(1,1,1-Trifluoro-2-Methylpropan-2-Yl)Pyridine is a specialized fluorinated pyridine derivative, identified by CAS number 1378865-93-0, valued for its unique trifluoromethylated tert-butyl side chain. This structural motif makes it a critical high-value building block in advanced organic synthesis, particularly for introducing steric bulk and fluorine atoms to modulate the properties of target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders or requiring metabolic stability.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Acts as a precursor for nitrogen-containing ligands in transition metal catalysis, useful in cross-coupling and other synthetic transformations.
• Material Science Research: Incorporated into organic frameworks or polymers to study the effects of fluorinated groups on material properties like hydrophobicity or dielectric constant.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research focused on the synthesis and reactivity of complex fluorinated heterocycles.

Basic Information

Product Name	4-Methyl-2-(1,1,1-Trifluoro-2-Methylpropan-2-Yl)Pyridine
CAS No.	1378865-93-0
Molecular Formula	C10H12F3N
Molecular Weight	203.21 g/mol
Synonyms	2-(1,1,1-Trifluoro-2-methylpropan-2-yl)-4-methylpyridine; 4-Methyl-2-(1,1,1-trifluoro-2-methyl-2-propyl)pyridine; 2-(1,1,1-Trifluoro-tert-butyl)-4-methylpyridine; 4-Methyl-2-(2,2,2-trifluoro-1,1-dimethylethyl)pyridine; α,α,α-Trifluoro-4-picoline-2-tert-butyl; 4-Methyl-2-(trifluoromethyl-tert-butyl)pyridine
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-(1,1,1-Trifluoro-2-Methylpropan-2-Yl)Pyridine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The compound is light-sensitive (store away from light) and may be sensitive to moisture; handle and store under inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.