Description

Bromomethanesulfonyl Fluoride is a specialized organosulfur compound that serves as a versatile and highly reactive building block in advanced chemical synthesis. Its unique bifunctional structure, containing both a bromomethyl group and a sulfonyl fluoride moiety, makes it an invaluable reagent for introducing the sulfonyl fluoride functional group into target molecules, a key step in developing pharmaceuticals and agrochemicals. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, chemical biology, and the synthesis of complex organic intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing sulfonamide or sulfonate ester functionalities.
• Chemical Biology Probe Development: Used in activity-based protein profiling (ABPP) and the development of covalent enzyme inhibitors due to the reactivity of the sulfonyl fluoride group.
• Agrochemical Synthesis: Employed in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Sulfonyl Fluoride Library Synthesis: A crucial building block for creating diverse compound libraries for high-throughput screening in drug discovery.
• Peptide and Protein Modification: Used for selective labeling or modification of peptides and proteins in bioconjugation chemistry.

Basic Information

Product Name	Bromomethanesulfonyl Fluoride
CAS No.	1378749-82-6
Molecular Formula	C2H4BrFO2S
Molecular Weight	191.02 g/mol
Synonyms	Bromomethylsulfonyl Fluoride; (Bromomethyl)sulfonyl Fluoride; Methanesulfonyl Fluoride, bromo-; α-Bromomethanesulfonyl Fluoride; Bromo(methyl)sulfonyl Fluoride; Sulfonyl Fluoride Bromomethane; Bromomethanesulfonic Acid Fluoride
EINECS	Contact for details

Quality Control

Our Bromomethanesulfonyl Fluoride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.