Description

Methyl 6-(Difluoromethoxy)Picolinate CAS NO 1375098-10-4 is a high-purity, advanced pharmaceutical intermediate characterized by its picolinate ester core and difluoromethoxy substituent. This compound matters as a critical building block in modern synthetic organic chemistry, enabling the development of novel active ingredients with enhanced properties. It is primarily needed by research and development teams and production units within the agrochemical and pharmaceutical industries for creating new crop protection agents and therapeutic molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drug discovery programs.
• Agrochemical Synthesis: Serves as a crucial precursor in the development of next-generation herbicides and fungicides, leveraging the difluoromethoxy group for improved bioactivity and stability.
• Chemical Research & Development: Used in academic and industrial R&D labs for method development and exploring new chemical entities.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical production and scale-up projects.
• Ligand and Catalyst Development: The picolinate moiety makes it a candidate for developing new metal-chelating ligands and catalysts in asymmetric synthesis.

Basic Information

Product Name	Methyl 6-(Difluoromethoxy)Picolinate
CAS No.	1375098-10-4
Molecular Formula	C8H7F2NO3
Molecular Weight	203.14 g/mol
Synonyms	Methyl 6-(difluoromethoxy)pyridine-2-carboxylate; 6-(Difluoromethoxy)picolinic Acid Methyl Ester; 2-Pyridinecarboxylic acid, 6-(difluoromethoxy)-, methyl ester; Methyl 6-(difluoromethoxy)-2-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 6-(Difluoromethoxy)Picolinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.