Description

2-(Difluoromethyl)-3,6-Difluoro-Pyridine is a specialized fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for introducing difluoromethyl and fluorine motifs into target molecules, which is critical for modulating the physicochemical and metabolic properties of compounds. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced potency and stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where fluorine atoms improve biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel fluorinated ligands used in catalysis and material science.
• Material Science Research: Employed in the synthesis of fluorinated organic electronic materials and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise fluorination.
• Academic and R&D Laboratories: Used in exploratory chemistry to study structure-activity relationships and develop new synthetic methodologies.

Basic Information

Item	Details
Product Name	2-(Difluoromethyl)-3,6-Difluoro-Pyridine
CAS No.	1374659-43-4
Molecular Formula	C6H3F4N
Molecular Weight	165.09 g/mol
Synonyms	3,6-Difluoro-2-(difluoromethyl)pyridine; 2-(Difluoromethyl)-3,6-difluoropyridine; Pyridine, 2-(difluoromethyl)-3,6-difluoro-; 1374659-43-4
EINECS	Contact for details

Quality Control

Every batch of 2-(Difluoromethyl)-3,6-Difluoro-Pyridine is manufactured under strict quality management systems. We employ advanced analytical techniques including GC, HPLC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its fluoride/strong alkali reactivity profile, ensure proper segregation in storage areas.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.