Description

1-(3-Chloro-5-Fluoropyridin-2-Yl)Ethanamine is a high-purity, advanced pharmaceutical intermediate featuring a halogenated pyridine core. This compound is of significant commercial importance as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing next-generation products.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, especially kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its halogenated pyridine structure for bioactivity.
• Ligand and Catalyst Development: Serves as a versatile starting material for creating specialized ligands used in catalytic processes and material science.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical entities and reaction pathways in medicinal chemistry.
• Custom Synthesis Building Block: Provides a functionalized scaffold for contract research organizations (CROs) and CDMOs to build custom molecules for client projects.

Basic Information

Product Name	1-(3-Chloro-5-Fluoropyridin-2-Yl)Ethanamine
CAS No.	1374652-12-6
Molecular Formula	C7H6ClFN2
Molecular Weight	172.59 g/mol
Synonyms	1-(3-Chloro-5-fluoropyridin-2-yl)ethan-1-amine; 1-(3-Chloro-5-fluoropyridin-2-yl)ethanamine; 2-(1-Aminoethyl)-3-chloro-5-fluoropyridine; Ethanamine, 1-(3-chloro-5-fluoro-2-pyridinyl)-; 3-Chloro-5-fluoro-2-(1-aminoethyl)pyridine; 1-(3-Chloro-5-fluoro-2-pyridinyl)ethanamine; 1-(3-Chloro-5-fluoropyridin-2-yl)ethylamine
EINECS	Contact for details

Quality Control

Our 1-(3-Chloro-5-Fluoropyridin-2-Yl)Ethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.