Description

2-Bromo-1,4-Dichloro-3-Fluorobenzene is a high-purity halogenated benzene derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, especially in fluorinated and halogenated active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the halogen pattern confers specific biological activity.
• Material Science Research: Serves as a precursor for liquid crystals, organic semiconductors, and other functional materials requiring precise halogen substitution.
• Cross-Coupling Reactions: An effective substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex, multi-substituted aromatic systems.

Basic Information

Product Name	2-Bromo-1,4-Dichloro-3-Fluorobenzene
CAS No.	1373233-32-9
Molecular Formula	C6H2BrCl2F
Molecular Weight	243.89 g/mol
Synonyms	1-Bromo-2,5-dichloro-4-fluorobenzene; 2,5-Dichloro-4-fluorobromobenzene; Benzene, 2-bromo-1,4-dichloro-3-fluoro-; 3-Fluoro-2-bromo-1,4-dichlorobenzene; 4-Fluoro-2-bromo-1,5-dichlorobenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-1,4-Dichloro-3-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.