Description

3-Fluoro-5-Methyl-Pyridine Hydrochloride is a high-purity, organofluorine building block essential for modern synthetic chemistry. This compound is valued for its role in introducing both fluorine and pyridine motifs into complex molecular architectures, enabling the fine-tuning of physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers and light-emitting components.
• Chemical Biology Probes: Utilized to create fluorinated probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Fluoro-5-Methyl-Pyridine Hydrochloride
CAS No.	1373223-28-9
Molecular Formula	C6H7ClFN
Molecular Weight	147.58 g/mol
Synonyms	5-Methyl-3-fluoropyridine hydrochloride; 3-Fluoro-5-picoline hydrochloride; 3-Fluoro-5-methylpyridine HCl; 3-Fluoro-5-methylpyridinium chloride; 5-Fluoro-3-methylpyridine hydrochloride (common numbering); Pyridine, 3-fluoro-5-methyl-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Methyl-Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality documentation to meet specific client and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.