Description

4-(4-Fluoro-Phenyl)-6-Methoxy-2H-Chromene-3-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate belonging to the chromene class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its chromene scaffold for bioactivity.
• Organic Synthesis Building Block: Serves as a versatile starting material for constructing more complex heterocyclic systems and fine chemicals in laboratory and pilot-scale production.
• Material Science Precursor: Investigated for use in the synthesis of organic light-emitting diodes (OLEDs) and other advanced functional materials due to its conjugated structure.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) settings for medicinal chemistry programs and structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-(4-Fluoro-Phenyl)-6-Methoxy-2H-Chromene-3-Carbaldehyde
CAS No.	1370470-34-0
Molecular Formula	C17H13FO3
Molecular Weight	284.28 g/mol
Synonyms	4-(4-Fluorophenyl)-6-methoxy-2H-chromene-3-carboxaldehyde; 6-Methoxy-4-(4-fluorophenyl)-2H-1-benzopyran-3-carbaldehyde; 4-(4-Fluorophenyl)-6-methoxy-2H-1-benzopyran-3-carbaldehyde; 3-Formyl-4-(4-fluorophenyl)-6-methoxy-2H-chromene; 4-(p-Fluorophenyl)-6-methoxy-2H-chromene-3-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-(4-Fluoro-Phenyl)-6-Methoxy-2H-Chromene-3-Carbaldehyde is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.