Description

2-Fluoro-5-Isopropoxynicotinic Acid is a high-value fluorinated nicotinic acid derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both fluorine and an isopropoxy group on the pyridine ring, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Precursor: Employed in the research of advanced organic electronic materials and liquid crystals.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Institutional Research: Used in universities and research institutes for methodological studies and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	2-Fluoro-5-Isopropoxynicotinic Acid
CAS No.	1370025-60-7
Molecular Formula	C9H10FNO3
Molecular Weight	199.18 g/mol
Synonyms	5-Isopropoxy-2-fluoronicotinic Acid; 2-Fluoro-5-(1-methylethoxy)-3-pyridinecarboxylic Acid; 3-Pyridinecarboxylic acid, 2-fluoro-5-(1-methylethoxy)-; 2-Fluoro-5-isopropoxy-3-pyridinecarboxylic Acid; 2-Fluoro-5-(propan-2-yloxy)nicotinic Acid; 1370025-60-7; 2-Fluoro-5-isopropoxynicotinic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Isopropoxynicotinic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee full traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.