Description

2-Bromo-4-Iodo-1-(Trifluoromethyl)Benzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring bromine, iodine, and a trifluoromethyl group on a benzene ring, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as cross-coupling reactions and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity often associated with halogenated and fluorinated compounds.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals with tailored electronic or optical properties.
• Cross-Coupling Reactions: The bromine and iodine substituents act as orthogonal handles for sequential Suzuki, Stille, or Sonogashira coupling reactions to build complex biaryl systems.
• Fluorine Chemistry: The trifluoromethyl group is a valuable, metabolically stable moiety in drug design, making this compound a crucial building block for medicinal chemistry programs.
• Chemical Synthesis Reference Standard: Used as a pure standard in analytical laboratories for method development and quality control of related synthetic pathways.

Basic Information

Product Name	2-Bromo-4-Iodo-1-(Trifluoromethyl)Benzene
CAS No.	1369927-31-0
Molecular Formula	C7H3BrF3I
Molecular Weight	350.90 g/mol
Synonyms	1-Bromo-3-Iodo-5-(Trifluoromethyl)Benzene; 2-Bromo-4-Iodo-α,α,α-Trifluorotoluene; 2-Bromo-4-Iodo-(Trifluoromethyl)Benzene; 3-Bromo-5-Iodobenzotrifluoride; 2-Bromo-4-Iodobenzotrifluoride; Benzene, 2-bromo-4-iodo-1-(trifluoromethyl)-; (2-Bromo-4-iodophenyl)(trifluoro)methane
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Iodo-1-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.