Description

5-Bromo-7-Fluoroisoquinoline is a high-purity halogenated isoquinoline derivative, a crucial building block in advanced organic synthesis. Its core value lies in its dual functionalization, providing reactive handles for cross-coupling and substitution reactions essential for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and anticancer research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the bioactivity of the fluorinated isoquinoline scaffold.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or charge-transport molecules.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.
• Cross-Coupling Reactions: Acts as a versatile substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to form biaryl structures.
• Ligand Synthesis: Employed in the preparation of complex chelating ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Bromo-7-Fluoroisoquinoline
CAS No.	1368250-42-3
Molecular Formula	C9H5BrFN
Molecular Weight	226.05 g/mol
Synonyms	7-Fluoro-5-bromoisoquinoline; Isoquinoline, 5-bromo-7-fluoro-; 5-Bromo-7-fluoro-isoquinoline; 1368250-42-3; 7-Fluoro-5-bromo-isoquinoline; 5-Br-7-F-Isoquinoline
EINECS	Contact for details

Quality Control

Our 5-Bromo-7-Fluoroisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee consistency and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.