Description

1-Bromo-2-Butoxy-4-(Trifluoromethyl)Benzene is a high-value, multi-functional aromatic building block designed for advanced chemical synthesis. This compound matters for its unique combination of bromine and trifluoromethyl substituents, which are critical for modulating the electronic and steric properties of target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated and fluorinated aromatic cores for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group is a privileged motif for efficacy.
• Liquid Crystal & OLED Materials: Acts as a building block for advanced electronic materials, where its aromatic structure and substituents help fine-tune electro-optical properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Functional Polymer Monomer: Employed in the synthesis of specialty polymers with tailored properties for high-performance coatings and engineering plastics.
• Organic Synthesis & Research: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	1-Bromo-2-Butoxy-4-(Trifluoromethyl)Benzene
CAS No.	1365272-77-0
Molecular Formula	C11H12BrF3O
Molecular Weight	297.11 g/mol
Synonyms	2-Bromo-1-butoxy-4-(trifluoromethyl)benzene; 4-Bromo-3-butoxybenzotrifluoride; 1-Butoxy-2-bromo-4-(trifluoromethyl)benzene; 2-Bromo-α,α,α-trifluoro-p-butoxytoluene; Benzene, 1-bromo-2-butoxy-4-(trifluoromethyl)-; [2-Bromo-4-(trifluoromethyl)phenoxy]butane
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Butoxy-4-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.