Description

4-Amino-3-Bromo-2-Fluoropyridine is a high-purity, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring amino, bromo, and fluoro substituents, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and electronic materials.
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Chemical Biology & Proteomics: Utilized as a versatile scaffold for designing molecular probes, enzyme inhibitors, and labeled compounds for diagnostic applications.

Basic Information

Product Name	4-Amino-3-Bromo-2-Fluoropyridine
CAS No.	1364917-17-8
Molecular Formula	C5H4BrFN2
Molecular Weight	191.00 g/mol
Synonyms	3-Bromo-2-fluoro-4-pyridinamine; 2-Fluoro-3-bromo-4-aminopyridine; 4-Pyridinamine, 3-bromo-2-fluoro-; 3-Bromo-2-fluoropyridin-4-amine; 4-Amino-2-fluoro-3-bromopyridine
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-3-Bromo-2-Fluoropyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.