Description

tert-Butyl 3,5-Difluoropyridin-4-Ylcarbamate is a high-purity, protected pyridine derivative designed for advanced synthetic chemistry. This compound serves as a critical building block in the development of complex molecules, particularly within the pharmaceutical sector. It is essential for researchers and process chemists in pharmaceutical R&D and fine chemical synthesis who require reliable, high-quality intermediates for constructing active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging the difluoropyridine moiety for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science: Employed in the research and synthesis of advanced organic electronic materials and functional polymers.
• Custom Synthesis & Contract Manufacturing: A vital starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic Research: Used in university and institutional labs for methodological studies in heterocyclic and fluorine chemistry.

Basic Information

Product Name	tert-Butyl 3,5-Difluoropyridin-4-Ylcarbamate
CAS No.	1364663-23-9
Molecular Formula	C10H12F2N2O2
Molecular Weight	230.21 g/mol
Synonyms	4-(((tert-Butoxy)carbonyl)amino)-3,5-difluoropyridine; tert-Butyl N-(3,5-difluoropyridin-4-yl)carbamate; 3,5-Difluoro-4-pyridinylcarbamic Acid 1,1-Dimethylethyl Ester; BOC-3,5-Difluoropyridin-4-amine; 4-N-Boc-amino-3,5-difluoropyridine; tert-Butyl (3,5-difluoropyridin-4-yl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3,5-Difluoropyridin-4-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.