Description

3-[[[3,5-Bis(Trifluoromethyl)Phenyl]Methyl]Amino]-4-[[(9R)-10,11-Dihydro-6'-Methoxycinchonan-9-Yl]Amino]-3-Cyclobutene-1,2-Dione is a sophisticated, high-purity organic compound featuring a cinchona alkaloid-derived chiral scaffold and a trifluoromethylated aromatic system. This molecular architecture makes it a valuable advanced intermediate or chiral ligand for asymmetric synthesis and pharmaceutical research. It is primarily targeted at research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers developing novel therapeutics and catalytic processes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for chiral molecules.
• Asymmetric Catalysis: Serves as a precursor or a chiral ligand for metal-catalyzed asymmetric reactions, such as hydrogenations or C-C bond formations.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies for drug discovery programs.
• Chemical Biology Probe: Potential utility in developing molecular probes to study enzyme mechanisms or biological pathways.
• Advanced Material Synthesis: Intermediate for creating specialized organic compounds with unique electronic or photophysical properties.

Basic Information

Item	Details
Product Name	3-[[[3,5-Bis(Trifluoromethyl)Phenyl]Methyl]Amino]-4-[[(9R)-10,11-Dihydro-6'-Methoxycinchonan-9-Yl]Amino]-3-Cyclobutene-1,2-Dione
CAS No.	1363811-07-7
Molecular Formula	C₃₅H₂₈F₆N₄O₃
Molecular Weight	666.62 g/mol
Synonyms	3-(((3,5-Bis(trifluoromethyl)benzyl)amino)-4-(((9R)-10,11-dihydro-6'-methoxycinchonan-9-yl)amino)cyclobut-3-ene-1,2-dione; (9R)-9-((4-(((3,5-Bis(trifluoromethyl)benzyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)-10,11-dihydro-6'-methoxycinchonan; Cinchona Alkaloid-Derived Cyclobutenedione; Chiral Cyclobutenedione Ligand Intermediate; CAS 1363811-07-7
EINECS	Contact for details

Quality Control

Our production of this high-value compound adheres to strict quality management protocols, ensuring batch-to-batch consistency and purity suitable for research and development applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.