Description

2-Methyl-2H-Indazole-4-Sulfonyl Chloride is a high-purity sulfonyl chloride derivative, a critical building block in modern synthetic chemistry. Its primary value lies in its reactivity as a versatile sulfonylation reagent, enabling the efficient synthesis of complex sulfonamides and other functionalized molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting kinase inhibition and other therapeutic pathways.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides by introducing the sulfonamide pharmacophore.
• Material Science Research: Employed in the creation of specialty polymers and functional materials requiring specific sulfonamide linkages.
• Chemical Biology Probes: Serves as a reactive handle for labeling proteins or modifying biomolecules in probe development.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses producing bespoke compounds for client R&D programs.

Basic Information

Product Name	2-Methyl-2H-Indazole-4-Sulfonyl Chloride
CAS No.	1363381-73-0
Molecular Formula	C8H7ClN2O2S
Molecular Weight	230.67 g/mol
Synonyms	2-Methyl-2H-indazole-4-sulfonyl chloride; 4-(Chlorosulfonyl)-2-methyl-2H-indazole; 2-Methyl-1,2-dihydroindazole-4-sulfonyl chloride; 2-Methylindazole-4-sulfonyl chloride; 1,2-Dihydro-2-methylindazole-4-sulfonyl chloride; 1363381-73-0; 2-Methyl-2H-indazol-4-ylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-2H-Indazole-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.