Description

4-Bromo-2-Methyl-2H-Indazole-3-Sulfonyl Chloride is a high-purity, advanced pharmaceutical intermediate and versatile chemical building block. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in drug discovery.
• Sulfonamide Derivative Synthesis: Used to introduce the sulfonyl chloride functional group, enabling the creation of various sulfonamide-based compounds with potential biological activity.
• Agrochemical Development: Employed in the research and synthesis of novel herbicides, fungicides, and other crop protection agents.
• Material Science: Can be utilized in the development of specialty polymers and functional materials requiring specific heterocyclic components.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Product Name	4-Bromo-2-Methyl-2H-Indazole-3-Sulfonyl Chloride
CAS No.	1363380-87-3
Molecular Formula	C8H6BrClN2O2S
Molecular Weight	309.57 g/mol
Synonyms	4-Bromo-2-methyl-2H-indazole-3-sulfonyl chloride; 2H-Indazole-3-sulfonyl chloride, 4-bromo-2-methyl-; 4-Bromo-2-methylindazole-3-sulfonyl chloride; 4-Bromo-2-methyl-1,2-dihydro-3H-indazole-3-sulfonyl chloride; 1363380-87-3; 4-Bromo-2-methyl-2H-indazole-3-sulfonoyl chloride; 4-Bromo-2-methylindazole-3-sulfonoyl chloride
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Methyl-2H-Indazole-3-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to GMP-grade standards and rigorous quality control ensures reliable performance for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.