Description

2-Methyl-2H-Indazole-7-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile electrophilic reagent for introducing the 2-methylindazole-7-sulfonyl moiety, enabling the construction of complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates, particularly in medicinal chemistry programs targeting new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific sulfonamide functionalities.
• Chemical Biology Probe Development: Employed in the creation of activity-based probes and affinity labels for studying enzyme function and protein interactions.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique properties.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical suppliers offering bespoke synthesis services for client-specific molecular targets.

Basic Information

Product Name	2-Methyl-2H-Indazole-7-Sulfonyl Chloride
CAS No.	1363380-68-0
Molecular Formula	C8H7ClN2O2S
Molecular Weight	230.67 g/mol
Synonyms	7-(Chlorosulfonyl)-2-methyl-2H-indazole; 2-Methyl-1H-indazole-7-sulfonyl chloride; 2-Methyl-2H-indazole-7-sulfonyl chloride; 1363380-68-0; 2-Methylindazole-7-sulfonyl chloride; 7-Chlorosulfonyl-2-methylindazole; 2-Methyl-2H-indazol-7-ylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-2H-Indazole-7-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.