Description

2-(Trifluoromethoxy)Pyridin-3-Ol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals due to the unique properties imparted by the trifluoromethoxy group. It is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced metabolic stability, lipophilicity, and biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy moiety improves efficacy and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and liquid crystals for electronic and optical applications.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and diagnostic applications.

Basic Information

Product Name	2-(Trifluoromethoxy)Pyridin-3-Ol
CAS No.	1361836-59-0
Molecular Formula	C6H4F3NO2
Molecular Weight	179.10 g/mol
Synonyms	3-Hydroxy-2-(trifluoromethoxy)pyridine; 2-(Trifluoromethoxy)-3-pyridinol; 3-Pyridinol, 2-(trifluoromethoxy)-; 2-Trifluoromethoxypyridin-3-ol; 2-(Trifluoromethoxy)-3-hydroxypyridine; α,α,α-Trifluoro-3-hydroxy-2-pyridinyl methyl ether
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethoxy)Pyridin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.