Description

(5-Fluoro-3-Methylpyridin-2-Yl)Methanol CAS NO 1360953-18-9 is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine atoms is a key strategy for modulating biological activity and metabolic stability. It is primarily needed by research and development chemists, process development teams, and manufacturers within the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine moiety for enhanced efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or metal-organic frameworks (MOFs) used in asymmetric catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers or liquid crystals where fluorinated aromatic units are required.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags or molecular probes in diagnostic and bioimaging applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluoropyridine motifs.

Basic Information

Product Name	(5-Fluoro-3-Methylpyridin-2-Yl)Methanol
CAS No.	1360953-18-9
Molecular Formula	C7H8FNO
Molecular Weight	141.14 g/mol
Synonyms	2-(Hydroxymethyl)-5-fluoro-3-methylpyridine; (5-Fluoro-3-methyl-2-pyridinyl)methanol; 5-Fluoro-3-methylpyridine-2-methanol; 2-Pyridinemethanol, 5-fluoro-3-methyl-; 5-Fluoro-3-methyl-2-pyridylmethanol
EINECS	Contact for details

Quality Control

Our (5-Fluoro-3-Methylpyridin-2-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.