Description

2-Chloro-1-(3-Fluoropyridin-2-Yl)Ethanone is a high-purity, halogenated pyridine derivative of significant interest in advanced organic synthesis. This compound serves as a critical versatile building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced organic electronic materials and functional polymers.
• Custom Synthesis and Contract Manufacturing: A valuable substrate for fine chemical manufacturers offering bespoke synthesis services to the pharmaceutical and biotechnology industries.

Basic Information

Product Name	2-Chloro-1-(3-Fluoropyridin-2-Yl)Ethanone
CAS No.	1357946-75-8
Molecular Formula	C7H5ClFNO
Molecular Weight	173.57 g/mol
Synonyms	2-Chloro-1-(3-fluoropyridin-2-yl)ethan-1-one; 2-Chloro-1-(3-fluoro-2-pyridinyl)ethanone; 1-(3-Fluoropyridin-2-yl)-2-chloroethanone; 2-Chloro-3'-fluoro-2-pyridyl ketone; α-Chloro-3-fluoro-2-pyridyl methyl ketone; 3-Fluoro-2-pyridyl chloromethyl ketone
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(3-Fluoropyridin-2-Yl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.