Description

5-Fluoro-3-(Methylsulfonyl)Pyridine-2-Carbaldehyde is a high-value, multi-functional pyridine derivative characterized by its reactive aldehyde group and electron-withdrawing substituents. This compound matters as a versatile and critical pharmaceutical intermediate for constructing complex bioactive molecules, particularly in medicinal chemistry. It is primarily needed by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for synthesizing novel drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in developing advanced pesticides and herbicides due to its bioactive pyridine core.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex heterocyclic compounds via its reactive aldehyde functionality.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	5-Fluoro-3-(Methylsulfonyl)Pyridine-2-Carbaldehyde
CAS No.	1357945-41-5
Molecular Formula	C7H6FNO3S
Molecular Weight	203.19 g/mol
Synonyms	2-Formyl-5-fluoro-3-methylsulfonylpyridine; 5-Fluoro-3-(methylsulfonyl)picolinaldehyde; 5-Fluoro-3-methanesulfonylpyridine-2-carboxaldehyde; 2-Pyridinecarboxaldehyde, 5-fluoro-3-(methylsulfonyl)-; 1357945-41-5
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-(Methylsulfonyl)Pyridine-2-Carbaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for sensitive synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle under an inert atmosphere for long-term storage of opened containers. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.