Description

1-((2S)-1-[(11Bs)-2,6-Dimethyldinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yloxy]Propan-2-Yl}-3-Phenylurea is a sophisticated chiral organophosphorus compound, representing a high-value intermediate in advanced chemical synthesis. Its complex, sterically hindered structure makes it a critical ligand or catalyst precursor for asymmetric transformations, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. This product is essential for R&D and manufacturing teams in the pharmaceutical, agrochemical, and specialty chemical sectors who require high-purity, specialized building blocks for process development and scale-up.

Application

• Asymmetric Catalysis: As a chiral ligand or precursor for transition metal catalysts in enantioselective hydrogenation, cross-coupling, and C-H activation reactions.
• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides for enhanced efficacy and environmental profile.
• Advanced Material Research: Potential component in the development of chiral polymers or molecular recognition systems.
• Process Chemistry: Employed in method development and optimization for the commercial-scale production of fine chemicals.
• Academic & Industrial R&D: A valuable reagent for exploring new methodologies in organometallic and synthetic organic chemistry.

Basic Information

Product Name	1-((2S)-1-[(11Bs)-2,6-Dimethyldinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yloxy]Propan-2-Yl}-3-Phenylurea
CAS No.	1357562-63-0
Molecular Formula	C₃₄H₃₁NO₄P
Molecular Weight	548.59 g/mol
Synonyms	(S)-1-(1-((11bS)-2,6-Dimethyldinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yloxy)propan-2-yl)-3-phenylurea; 1-[(2S)-1-[(11bS)-2,6-Dimethyldinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]oxypropan-2-yl]-3-phenylurea; Chiral BINOL-Derived Phosphite Urea Ligand; Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin Urea Derivative; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our production of this high-purity chiral compound adheres to strict quality management protocols. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to ensure chemical identity, enantiomeric purity, and lot-to-lot consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.