Description

2-(1,1,1-Trifluoro-2-Methylpropan-2-Yl)Pyridin-4(1H)-One is a high-value fluorinated pyridinone derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in the unique trifluoromethylated tert-butyl moiety, which imparts enhanced metabolic stability and lipophilicity to target molecules, making it indispensable for research and development. This compound is primarily sought by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, including potential kinase inhibitors and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the fluorine atoms for improved bioactivity and environmental profile.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials where the introduction of fluorine groups is required.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up services for clients in the fine chemical industry.

Basic Information

Product Name	2-(1,1,1-Trifluoro-2-Methylpropan-2-Yl)Pyridin-4(1H)-One
CAS No.	1357476-66-4
Molecular Formula	C9H10F3NO
Molecular Weight	205.18 g/mol
Synonyms	4(1H)-Pyridinone, 2-(1,1,1-trifluoro-2-methyl-2-propanyl)-; 2-(1,1,1-Trifluoro-2-methylpropan-2-yl)-1,4-dihydropyridin-4-one; 2-(1,1,1-Trifluoro-2-methylprop-2-yl)pyridin-4(1H)-one; 2-(Trifluoro-tert-butyl)pyridin-4(1H)-one; 2-(Perfluoro-tert-butyl)-4-pyridone; 4-Hydroxy-2-(1,1,1-trifluoro-2-methyl-2-propyl)pyridine
EINECS	Contact for details

Quality Control

Our production of 2-(1,1,1-Trifluoro-2-Methylpropan-2-Yl)Pyridin-4(1H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.