Description

C-Met Inhibitor 1 CAS NO 1357072-61-7 is a potent and selective small molecule inhibitor targeting the c-Met (mesenchymal-epithelial transition factor) tyrosine kinase receptor. This compound is a critical research tool for investigating signaling pathways involved in cell proliferation, survival, and motility, which are often dysregulated in various cancers. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in oncology drug discovery and preclinical studies.

Application

• Oncology Research & Drug Discovery: A key biochemical tool for studying the role of c-Met/HGF signaling in tumor growth, metastasis, and resistance mechanisms.
• Preclinical In Vitro Studies: Used in cell-based assays to evaluate the efficacy and selectivity of c-Met inhibition on cancer cell lines.
• Mechanism of Action (MoA) Studies: Essential for elucidating downstream signaling pathways (e.g., PI3K/Akt, MAPK/ERK) activated by c-Met.
• High-Throughput Screening (HTS): Serves as a reference compound or positive control in screening campaigns for novel c-Met inhibitors.
• Biomarker Research: Used in studies to identify predictive biomarkers for c-Met-targeted therapies.
• Chemical Probe Development: Acts as a starting point or comparator in the design and synthesis of more potent or selective chemical probes.

Basic Information

Product Name	C-Met Inhibitor 1
CAS No.	1357072-61-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	c-Met inhibitor 1; c-Met Inhibitor 1; CAS 1357072-61-7; 1357072-61-7; c-Met tyrosine kinase inhibitor 1; Mesenchymal-epithelial transition factor inhibitor 1; Hepatocyte growth factor receptor inhibitor 1; MET inhibitor 1
EINECS	Contact for details

Quality Control

Our C-Met Inhibitor 1 is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including purity verification by HPLC and structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your regulatory and documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.