Description

n-Acetyl-S-(2-Hydroxypropyl)Cysteine-D3 Dicyclohexylammonium Salt is a high-purity, deuterium-labeled internal standard critical for advanced analytical quantification. This compound is specifically designed for precise and reliable mass spectrometry analysis, offering superior accuracy in trace-level detection. It is an essential reagent for researchers and quality control laboratories in the pharmaceutical, biotechnology, and contract research organization (CRO) sectors, particularly for metabolomic studies and bioanalytical method development.

Application

• Internal Standard for LC-MS/MS: Primary use as a quantitative internal standard in liquid chromatography-tandem mass spectrometry for accurate measurement of related cysteine metabolites or drug conjugates.
• Biomarker Research: Enables precise tracking and quantification in studies of oxidative stress, detoxification pathways (e.g., mercapturic acid pathway), and biomarker discovery.
• Drug Metabolism and Pharmacokinetics (DMPK): Critical for the bioanalysis of drug metabolites, supporting ADME (Absorption, Distribution, Metabolism, and Excretion) studies in preclinical and clinical research.
• Toxicology and Exposure Assessment: Used to quantify human exposure to industrial chemicals or environmental toxins by measuring specific mercapturic acid derivatives in biological fluids.
• Stable Isotope Labeling: Serves as a deuterium-labeled reference compound for method validation and ensuring data integrity in regulated environments.

Basic Information

Product Name	n-Acetyl-S-(2-Hydroxypropyl)Cysteine-D3 Dicyclohexylammonium Salt
CAS No.	1356934-59-2
Molecular Formula	C14H27D3N2O4S
Molecular Weight	313.48 g/mol (for monoisotopic mass)
Synonyms	N-Acetyl-S-(2-hydroxypropyl)-L-cysteine-d3 dicyclohexylammonium salt; N-Acetyl-S-(2-hydroxypropyl)cysteine-d3 dicyclohexylamine salt; 2-(Acetylamino)-3-[[(2-hydroxypropyl)sulfanyl]-D3]propanoic acid dicyclohexylammonium salt; HPMA-d3 (Deuterated N-Acetyl-S-(2-hydroxypropyl)cysteine) dicyclohexylammonium salt; Deuterated Mercapturic Acid Derivative Standard; N-Acetyl-S-(2-Hydroxypropyl)-L-cysteine (Deuterated, d3) Dicyclohexylammonium Salt; Internal Standard for HPMA
EINECS	Contact for details

Quality Control

Every batch of our n-Acetyl-S-(2-Hydroxypropyl)Cysteine-D3 Dicyclohexylammonium Salt is manufactured and analyzed under strict quality systems to ensure identity, purity, and isotopic enrichment meet the exacting standards required for analytical research. We provide comprehensive Certificates of Analysis (COA) detailing specifications for isotopic purity (D3 content), chemical purity (by HPLC), and identification. Our quality commitment supports compliance needs for GLP (Good Laboratory Practice) and GMP (Good Manufacturing Practice) environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This compound is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.